00719nas a2200217 4500008004100000245009200041210006900133260003300202100002200235700002400257700001600281700002300297700001500320700001400335700002200349700002600371700002100397700001300418700001900431856005100450 2015 en d00aThe phototransduction machinery in the rod outer segment has a strong efficacy gradient0 aphototransduction machinery in the rod outer segment has a stron bNational Academy of Sciences1 aMazzolini, Monica1 aFacchetti, Giuseppe1 aAndolfi, L.1 aZaccaria, Proietti1 aTuccio, S.1 aTreud, J.1 aAltafini, Claudio1 aDi Fabrizio, Enzo, M.1 aLazzarino, Marco1 aRapp, G.1 aTorre, Vincent uhttp://urania.sissa.it/xmlui/handle/1963/3515701565nas a2200169 4500008004100000245010100041210006900142260001000211520092400221100002201145700002401167700002201191700001701213700001901230700002201249856012401271 2013 en d00aCommon dynamical features of sensory adaptation in photoreceptors and olfactory sensory neurons.0 aCommon dynamical features of sensory adaptation in photoreceptor bSISSA3 a
Sensory systems adapt, i.e., they adjust their sensitivity to external stimuli according to the ambient level. In this paper we show that single cell electrophysiological responses of vertebrate olfactory receptors and of photoreceptors to different input protocols exhibit several common features related to adaptation, and that these features can be used to investigate the dynamical structure of the feedback regulation responsible for the adaptation. In particular, we point out that two different forms of adaptation can be observed, in response to steps and to pairs of pulses. These two forms of adaptation appear to be in a dynamical trade-off: the more adaptation to a step is close to perfect, the slower is the recovery in adaptation to pulse pairs and viceversa. Neither of the two forms is explained by the dynamical models currently used to describe adaptation, such as the integral feedback model.
1 aDe Palo, Giovanna1 aFacchetti, Giuseppe1 aMazzolini, Monica1 aMenini, Anna1 aTorre, Vincent1 aAltafini, Claudio uhttps://www.math.sissa.it/publication/common-dynamical-features-sensory-adaptation-photoreceptors-and-olfactory-sensory